Firm wins $65 million contract for botulism treatments

first_img The contract is the third one that the National Institute of Allergy and Infectious Diseases (NIAID) has awarded Xoma to develop botulism antitoxins, the company said in a Sep 9 statement. In 2005 Xoma was among the first companies to receive a contract through Project BioShield, according to a previous report. Xoma reported that  its NIAID contracts cover the development of human monoclonal antibody products targeting the three most toxic serotypes of botulinum toxin, types A, B,and E. The company also said these human antibody products are expected to be safer than existing animal-derived antibodies, which it said cause serious immune reactions in some patients and vary unpredictably in their efficacy. See also: Sep 11, 2008 (CIDRAP News) – Xoma Ltd., a Berkeley, Calif., pharmaceutical company, recently announced that it received a $65 million multiyear federal contract to fund work on botulinum antitoxins, one of which it hopes to put through safety and efficacy tests starting in 2009. Clostridium botulinum, which produces botulinum toxin, a nerve poison, is among the category A agents that experts say bioterrorists would most likely try to use. However, most botulism cases are caused by tainted food or contaminated wounds. Sep 9 Xoma press release Steven Engle, Xoma’s chairman and chief executive officer, said in the statement that the contract shows the US government’s support of novel therapies that address natural, accidental, or intentional infections from pathogens and their toxins. “Since initiating its biodefense program in 2005, Xoma has used its innovative antibody technology to develop better and safe solutions,” he said. “We plan to continue working with the government’s biodefense development efforts toward future stockpiling initiatives.” Xoma said if studies show that the company’s first botulism antitoxin candidate is safe and effective and government funding continues, it would file the paperwork needed to produce the treatment for the Strategic National Stockpile. The new NIAID contract will cover the next 6 years of botulism antitoxin development, the company said. May 10, 2005, CIDRAP News story “NIAID awards first Project BioShield grants”last_img read more

Battle For Premier League Promotion: Championship Leaders Suffer Shock Defeat

first_imgEnglish championship leaders Cardiff City suffered only their second league defeat of the season following a surprising 1-0 defeat at struggling Birmingham City.The only goal of the game was scored by Che Adams in the 19th minute in what was Steve Cotterill’s first game in charge of Birmingham City and the result was enough for the team to climb out of the relegation zone.In the other league game on Friday night, Burton Albion recorded a third successive clean sheet away from home as they kept their hosts Bristol City at bay in a goalless draw affair at Ashton Gate. Bristol City missed out on the opportunity to move into second position with a win.A win for Neil Warnock’s Cardiff City would have taken the team four points clear of Wolverhampton Wanderers in second place. The leaders are still occupying the top spot with 24 points from their first 12 league games of the season.RelatedThe Big Seven Matches This WeekendMarch 10, 2018In “England”The Big Seven Matches This WeekendFebruary 9, 2018In “England”Middlesbrough FC vs Southampton FCJune 30, 2017Similar postlast_img read more

March Madness 2019: Texas Tech’s Tariq Owens returns after suffering leg injury vs. Michigan State

first_img March Madness 2019: Auburn’s Bruce Pearl addresses last-second foul call vs. Virginia Texas Tech avoided a major problem.Tariq Owens, who had tallied several big blocks in the tournament and in the Red Raiders’ matchup with Michigan State in the Final Four, went down after twisting his ankle badly in the second half. Tariq Owens with a thunderous jam #4To1 #FinalFour— Sports Daily (@SportsDGI) April 7, 2019After a few minutes in the locker room Owens jogged back out to the bench to the delight of the Red Raider faithful.He came back into the game with 6:52 left in the game.The Red Raiders’ crowd goes wild as Tariq Owens returns from the locker room after an injury! 👏@TexasTechMBB | #FinalFour— NCAA March Madness (@marchmadness) April 7, 2019This story will be updated. Owens had seven points, four rebounds and three blocks when he went out.center_img March Madness 2019: Virginia tops Auburn after devastating foul call on 3-pointer Tariq Owens sends Texas Tech into the break with a two-point lead on Michigan State!— SI College Hoops (@si_ncaabb) April 7, 2019Owens appeared to twist both his ankle and his knee and stayed down on the floor for a few minutes.He was able to get up and walk off the floor on his own power. Related Newslast_img read more

St George’s College mourns – ISSA responds to student’s death

first_img “I know this is really going to take a toll. I have been touching base with some of the principals, and we are looking to get to St George’s tomorrow (today) to share, and I am trying to get the Ministry (of Education) to bring in a few of their counsellors because it’s going to be a very tough moment for everyone, therefore, we are going to make all efforts to ensure people are there to offer some support,” added Small. Still, the fact that James was taken to hospital in his father’s vehicle has again raised questions about the inadequate medical support at local schoolboy football games. “We are aware. For example, we know there are a lot of matches being played in this round, and even if you are to get all the ambulances in Jamaica at the venues, we would not have enough ambulances, therefore, what we encourage the schools to do is to make arrangements with the nearest hospital or medical facility,” said Small. “When we get to the second round when ISSA takes over (the running of each game), because these (first round) matches are in the ambit of the schools, we ensure that we have ambulances where possible,” Small said. “At this level, it is impossible to have each school having an ambulance at the field since we are playing so many matches.” The executive of the Inter Secondary Schools Sports Association (ISSA) is expected to meet today to discuss the way forward, after yesterday’s sudden death of St George’s College student Dominic James during a Manning Cup football match. James, who was the team’s captain, collapsed approximately four minutes into yesterday’s game against Excelsior High at Stadium East and was later pronounced dead at the University Hospital of the West Indies. ISSA President Dr Walton Small, who expressed shock and sadness at the youngster’s passing, sought also to explain why there was no ambulance stationed at the venue and noted that the next set of Manning Cup fixtures might be suspended, while the executive looks to ensure sufficient support for those affected by the tragedy. “We want to express condolences to the family. I also want to express condolence to the St George’s family, it’s really a shock, and we are all in mourning at this moment,” Small told The Gleaner yesterday afternoon. “We (ISSA executive) were supposed to meet on Thursday, but I am looking to call an emergency meeting tomorrow (today). “I have not yet spoken to my peers, but there might be a moment of silence at the upcoming matches. We will look at postponing the next set of Manning Cup matches, but again, I have not yet spoken to the executive,” added Small. COUNSELLING FOR STUDENTSlast_img read more