ZMapp Drugs ‘Cured’ 100 Monkeys

first_imgMultiple news agencies announced Saturday, that ZMapp had cured 100 percent of monkeys that were inoculated with a different strain of Ebola in a Canadian study of the virus.According to researchers, health officials and medical teams, the vaccine has not undergone the normal human clinical trial stages. However, a small handful of infected people agreed to be injected with the vaccine.CBCNews.com reported yesterday that one Ebola survivor now pleads with the vaccine manufacturer to hurry with the production of the drug.The drug that is being referred to as a “monumental achievement,” only had about 20 doses in stock, and all have been exhausted.Researchers said once a living host has been sick for too long, there are those instances wherein possible treatments cannot turn back the damage already done to the body by the hemorrhagic virus.According to USA Today, a newspaper circulated across that country, of the small amount of people who have received the vaccine, only two have died.  These were “a Spanish priest and a Liberian doctor.” This  means it could be that they may have received the vaccine too late, the newspaper said.The monkeys which were given a lethal strain of Ebola recovered, and were given the drug five days after infection.With only a small number of Ebola patients testing the drug, it is hard for researchers to conclude whether it is the main reason for the patient’s recovery.In the wake of numbers of Ebola cases increasing in West Africa, health officials, medical teams and pharmaceutical researchers have scrambled to find a treatment of the virus to help reduce and contain the spread of the epidemic in the West African affected countries.Thomas Geisbert, an Ebola expert, said one of the infected Americans, Kent Brantly, didn’t just receive the vaccine but he also had a blood transfusion from an Ebola patient who survived — so his case isn’t one hundred percent ZMapp.The research report,  published in the Journal Nature, states that humans should receive three scheduled doses to optimize the efficacy for recovery. While the World Health Organization (WHO) has estimates that the current outbreak will infect more than 18,000 people, Gary Kobinger, who works for Canada’s Public Health Agency, said the drug is manufactured by a bio processing plant in Kentucky, and can only produce 20 to 40 doses per month. But the question remains, does Zmapp work for humans? Kobinger told The Washington Post, “I think it strongly supports that concept, but it’s not proven.”The spokesman for the owner of the Kentucky Bio processing plant believes that the three doses are theory.  Since conclusive human studies have not been done, the real issue is to have everyone’s focus on the clinical, and development steps to help find the correct dosing requirements, and speed up processing, he said.ZMapp could obtain approval of the United States Food and Drug Administration (FDA) in six month, maybe less, under their accelerated review titles.So far, Kobinger said, none of the animals tested has  shown any side effects. He also indicated that the Zaire Ebola strain now appears to be mutating as it moves from host to host, and researchers can’t be sure that Zmapp will solve the Ebola problem.Share this:Click to share on Twitter (Opens in new window)Click to share on Facebook (Opens in new window)last_img read more

CARBON MONOXIDE ALARMS TO FITTED TO ALL COUNCIL DWELLINGS

first_imgCarbon Monoxide alarms will now be installed in all council dwellings having works carrie rout under the insulation programme.Cllr Jimmy KavanaghThe move has been welcomed by Councillor Jimmy Kavanagh who was informed of the development by Donegal County Council.It follows a review in 2014 of the fitting of alarms. The alarms will also be fitted where vacant properties are being returned to use.It is intended that all of the councils rented properties will be upgraded over the next few years. CARBON MONOXIDE ALARMS TO FITTED TO ALL COUNCIL DWELLINGS was last modified: April 25th, 2015 by StephenShare this:Click to share on Facebook (Opens in new window)Click to share on Twitter (Opens in new window)Click to share on LinkedIn (Opens in new window)Click to share on Reddit (Opens in new window)Click to share on Pocket (Opens in new window)Click to share on Telegram (Opens in new window)Click to share on WhatsApp (Opens in new window)Click to share on Skype (Opens in new window)Click to print (Opens in new window) Tags:carbon monoxide alarmsCllr Jimmy Kavanaghdonegallast_img read more

Trapping sense

first_imgShare Facebook Twitter Google + LinkedIn Pinterest My most fragrant weekend ever occurred when I worked for the Columbus-based Sportsmen’s Alliance, at the time called the Wildlife Legislative Fund of America. The pro-trapping organization had me man an exhibit booth at the annual National Trappers Association convention at a county fairgrounds in Indiana, where I shared a long, hot September weekend with dozens of trappers displaying their home-brewed scents inside a poorly ventilated, oversized Quonset hut. After two 10-hour days confined with that crew and their pungent wares, it took multiple washings to get the stank of castor-based concoctions out of the clothes I wore, and even my car’s interior retained the scent for more than a week afterward. To this day, the slightest hint of skunk takes me back to those fragrant fairgrounds.Similar scents, albeit less-concentrated than those I endured, may be on the breeze at the Holmes County fairgrounds early this month, during the annual gathering of Ohio State Trappers Association members in Millersburg. The event is open to the public and offers the chance to see professional trappers in action as they lead talks on various techniques that are used for maintaining a sense of balance in Ohio’s furbearer populations. Ohio State Trappers conveneThe 2017 Ohio State Trappers Association Convention will be held September 8-9 at the Holmes County Fairgrounds, 8880 OH Route 39, in Millersburg.  The event and programs are open to the public, and adults pay a $5 entry fee. Kid’s events and an outdoor flea market are ongoing, with an auction held Saturday night. Here is the schedule of demonstrations and their presenters:Friday, Sept. 88 a.m. — Jake Meadows, Fox Trapping9 a.m. — Dave and Karen Linkhart, Team Trapping10 a.m. — Glenn Witchey, Raccoon & Coyote Trapping11 a.m. — Charlie Pierce, Mink TrappingNoon — Butch Barhorst, Coyote Trapping1 p.m. — Dirk Schearer, Nuisance Trapping2 p.m. — Dave Rodgers, K9s and Bobcats3 p.m. — Scott Welch, Trapline Troubleshooting4 p.m. — Harry Kinnison, DP Traps Saturday, Sept. 98 a.m. — Jim Cundiff, Coyote Trapping9 a.m. — Doug Lee, Muskrat Trapping10 a.m. — Jason Webster, Raccoon Trapping11 a.m. — Jeff Robinson, K9 and Bobcat TrappingNoon — Robby Gilbert, Coyote Trapping1 p.m. —  Keith Daniels, Turtle Trapping/Processing2 p.m. — Dave Muir, Trap Regs/Legal Trap Mods3 p.m. — Hal Sullivan, Beaver Trapping4 p.m. — Sam Luther, GinsengFor more information on the annual convention, visit ohiostatetrlast_img read more

Stabilizing Your Camera Movement: Gimbals vs. Steadicams

first_imgEvery cinematographer knows the quest for smooth footage. Let’s take a look at two of the primary options for stabilizing footage during production.Both the Steadicam and Gimbal (like the Movi or the Ronin) will eliminate the shake from your camera shots. They do so in very different ways, and at different costs. So, let’s take a look at the differences between them and how best to use each type of stabilizer.The Steadicam was invented in 1975 to free the 35mm film camera from a dolly or a tripod. It quickly won an Oscar for technical innovation, and it still shows up on film sets 45 years later. It’s a mechanical solution, and because it relies on inertia, it needs a heavy payload for smooth motion. The part that holds the camera — the sled — also holds the monitor and batteries.An operator wears a vest to distribute the weight to his or her shoulders and hips, and connects the camera sled to an Iso-elastic arm (with a series of springs) that isolate his movements from the camera.Enter the GimbalThe gimbal, first popularized by Movi in 2013, is an electronic solution. The technology appeared years before in helicopter mounts and crane arms. However, it wasn’t until digital cinema cameras under 10 pounds appeared that a handheld gimbal became viable. The camera gimbal works by measuring the camera’s position hundreds of times per second, and when it detects a movement, it engages motors to move an equal degree in the opposite direction, thereby negating the shake.Image via Movi.Like a lot of gear that relies on computers, brushless gimbals have lots of points of failure, but they also have a quick improvement curve. Gimbals get lighter, stronger, and more capable every year, whereas the Steadicam is still basically the same four decades later. So, what are the relative strengths and weaknesses of each one?Gimbals are cheaper, quicker to set up, and easier to use. You’ll notice I said, quicker and easier, not quick and easy. They still have a learning curve. It takes time and practice to become proficient with one, especially with heavier cameras. A Movi Pro or Ronin 2 will cost you around $6,500. You might also need a few other accessories, like batteries and mounts, but you’ll probably spend less than $8,000. A full Steadicam setup will set you back $45,000, but you can hire an operator with their own rig (in most cities) for $1,000/day.One thing a Steadicam compensates for — and a gimbal does not — is the up-and-down movement of walking. When walking with a gimbal, you need to bend your knees and do what’s commonly referred to as the “duck walk” — a shuffle that limits vertical bobbing. This limits just how fast you can move, while keeping the motion smooth.The Right Tool for the JobA Steadicam — despite being more expensive, taking longer to set up, and requiring more skill to operate — has advantages over the gimbal. Because the Steadicam isn’t supported entirely by the operator’s arms, the shots can be longer, and the operator can do more takes in a row before their performance starts to suffer. Famous Steadicam takes are minutes long, and a trained operator can do take after take without needing a break.Image via Steadicam.The Steadicam, being mechanical, doesn’t need batteries, and it doesn’t have electronic issues, like firmware updates. Many a gimbal shoot has ended in tears when the gimbal software crashed and couldn’t be restarted.A Hybrid FutureI should mention that hybrid systems have appeared in recent years that try to combine elements from both stabilizers — a gimbal on a Steadicam like an arm. These give you the best of both worlds, but also the worst of both worlds. They are more expensive and need much longer to set up than either system alone. But once they do work, they can deliver shots that were once thought impossible. ARRI has a system called the Trinity that can do amazing things. The price: $65,000.Both systems have different strengths and weaknesses. Thus, the more you pre-plan your shots and know what kind of motion you’re after, the better. If you want to fly a heavy camera or use long take times, you’re looking at hiring a Steadicam operator. If your camera is smaller and lighter, and you can plan to shoot for a minute or less, you can save money by renting a gimbal and learning to use it yourself — or hiring one that comes with an operator.Cover image via United Artists.Looking for more cinematography and filmmaking articles? Check these out.The History and Power of Sound Design in the Film Industry6 Slow Motion Cameras You Can AffordProduction Tips: Working With a Color Checker on Your Next ShootAdd Flavor to Your Footage by Implementing Color ScienceFilmmaking Fads and Trends: Don’t Let Them Bother Youlast_img read more