Firm wins $65 million contract for botulism treatments

first_img The contract is the third one that the National Institute of Allergy and Infectious Diseases (NIAID) has awarded Xoma to develop botulism antitoxins, the company said in a Sep 9 statement. In 2005 Xoma was among the first companies to receive a contract through Project BioShield, according to a previous report. Xoma reported that  its NIAID contracts cover the development of human monoclonal antibody products targeting the three most toxic serotypes of botulinum toxin, types A, B,and E. The company also said these human antibody products are expected to be safer than existing animal-derived antibodies, which it said cause serious immune reactions in some patients and vary unpredictably in their efficacy. See also: Sep 11, 2008 (CIDRAP News) – Xoma Ltd., a Berkeley, Calif., pharmaceutical company, recently announced that it received a $65 million multiyear federal contract to fund work on botulinum antitoxins, one of which it hopes to put through safety and efficacy tests starting in 2009. Clostridium botulinum, which produces botulinum toxin, a nerve poison, is among the category A agents that experts say bioterrorists would most likely try to use. However, most botulism cases are caused by tainted food or contaminated wounds. Sep 9 Xoma press release Steven Engle, Xoma’s chairman and chief executive officer, said in the statement that the contract shows the US government’s support of novel therapies that address natural, accidental, or intentional infections from pathogens and their toxins. “Since initiating its biodefense program in 2005, Xoma has used its innovative antibody technology to develop better and safe solutions,” he said. “We plan to continue working with the government’s biodefense development efforts toward future stockpiling initiatives.” Xoma said if studies show that the company’s first botulism antitoxin candidate is safe and effective and government funding continues, it would file the paperwork needed to produce the treatment for the Strategic National Stockpile. The new NIAID contract will cover the next 6 years of botulism antitoxin development, the company said. May 10, 2005, CIDRAP News story “NIAID awards first Project BioShield grants”last_img read more

Man called Garda station from Australia threatening to rape and kill Gardai

first_imgA man telephoned Gardai from Australia and threatened to rape and kill a number of them and their children and then mocked their dead colleague killed in the line of duty.Twisted Mark Fair had skipped bail in Ireland and had travelled to Australia to work. However, over a period of around seventeen days in January 2015, he bombarded Buncrana Garda Station in Co Donegal with a series of obscene phonecalls.Officers could tell it was Fair as they had dealt with him before but he continued to make threats against them and their families.The now 28-year-old appeared at Letterkenny Circuit Court where he pleaded guilty to a total of eleven counts of making threats to kill, threats to damage property and also making grossly offensive phonecalls.The calls were made to Garda Una Cunningham, Garda Grainne McLoone, Elaine Moyles, Lorraine Crawford and Sgt Carol Doherty.Details of the shocking calls made by Fair, of Ballinahone, Fahan, were read out in court.Fair first began his ant of abusive phonecalls on January 10th when he called Garda Elaine Moyles.He recognised her voice and told her he was going to shoot her in the back of the head and also kill her husband.He also asked how Gary McLoughlin was and said he was going to land at Buncrana Garda station and pull the plaque off the wall which was dedicated to Gary.Tragic Garda Gary McLoughlinThe former Garda McLoughlin, aged just 24, was killed in the line of duty in Co Donegal in December 2009.Fair called the Garda station at a later date and spoke to Garda Grainne McLoone and said he was going to rape her and her children and that he hoped her mother died of cancer.He pretended his name was Martin McDermott, a man charged in connection with the death of the late Garda McLoughlin.On January 12th, Fair called the station again and told Garda Lorraine Crawford that he would bend her over and ride her before going on to say he would rape her son and sister “just for sport.”On another date, he called the station and asked Garda Sgt Carol Doherty if Garda McLoughlin was there which caused her great upset.And on January 27th, Fair called the station again and he spoke to Garda Una Cunningham.He said he would show her his cock in court and that he was going to rape her dog.He asked Garda Cunningham if she wanted to suck his cock and that he was going to raise Garda Gary McLoughlin from the dead.A victim impact statement on behalf of all the Gardai who received abusive calls from Fair was compiled by Sgt Carol Doherty and was handed into Judge John Aylmer but not read in open court.As well as the litany of abusive phonecalls and threats, Fair also pleaded guilty to eleven counts of making gain or causing deception using Donedeal.Over a two month period from February to March in 2018, Fair placed fraudulent adverts on the free ads website and also replied to adverts.Letterkenny Court.Among the items he advertised or responded to as having for sale was tickets for the Champions League Final, iPhones, tractor parts, gearboxes and car bumpers.However, when the cash for the items sent to various accounts belonging to Fair, the goods were never forwarded on.In total Fair admitted defrauding people from across the country out of more than €3,000.When arrested Fair admitted that he used a ‘fraud phone’.He apologised to all those he had defrauded money from and said he had already compensated two of the victims.Barrister for Fair, who had 36 previous convictions, Mr Peter Nolan said there was simply no explanation for what he had done.He revealed how he was from a respectable farming family and that his six siblings, three brothers and three sisters, had never been in trouble with the law.He said that when he was making the phonecalls from Australia his client was drunk and was in the company of other young men from the Buncrana area of Donegal.Fair got into the witness box and apologised to the female Gardai and said he never planned to carry out any of his threats.He added “I don’t remember making them (the threats) I was so drunk. I thought it was funny at the time but it’s not funny now.“I’d like to apologise to all the Gardai as nothing I said was true and it wasn’t going to be carried out.”Barrister Peter Nolan said his client was a fantasist and claims that he was living the high life in hotels such as the Gresham in Dublin for the proceeds of his crime were not true.He said his client was now in custody for seven months and that he was a model prison in the prison and was working in the kitchen.Fair’s mother was also in court but said she did not want to address the court.Judge John Aylmer adjourned the case until Friday when he will sentence Fair.Man called Garda station from Australia threatening to rape and kill Gardai was last modified: August 1st, 2019 by StephenShare this:Click to share on Facebook (Opens in new window)Click to share on Twitter (Opens in new window)Click to share on LinkedIn (Opens in new window)Click to share on Reddit (Opens in new window)Click to share on Pocket (Opens in new window)Click to share on Telegram (Opens in new window)Click to share on WhatsApp (Opens in new window)Click to share on Skype (Opens in new window)Click to print (Opens in new window)last_img read more

GAA: GLENSWILLY CLUB NEWS

first_imgThe monthly club meeting will take place on Monday 14th May at 8.15pm.Can everyone who is using the hall please ensure that it is locked when they are finished using it, All bookings for the hall or clubrooms must be made through Karen McHugh.Operation Fitness continues with a weigh Wednesday at 7pm, circuits on Monday and walk on Saturday morning still time to join if you want to lose weight or get fit! Gym is women only from 7pm to 9pm Monday, Wednesday and fridayPlease see local papers for fixtures for this weekend.GAA: GLENSWILLY CLUB NEWS was last modified: May 8th, 2012 by StephenShare this:Click to share on Facebook (Opens in new window)Click to share on Twitter (Opens in new window)Click to share on LinkedIn (Opens in new window)Click to share on Reddit (Opens in new window)Click to share on Pocket (Opens in new window)Click to share on Telegram (Opens in new window)Click to share on WhatsApp (Opens in new window)Click to share on Skype (Opens in new window)Click to print (Opens in new window) Tags:Glenswilly GAA Club noteslast_img read more