Firm wins $65 million contract for botulism treatments

first_img The contract is the third one that the National Institute of Allergy and Infectious Diseases (NIAID) has awarded Xoma to develop botulism antitoxins, the company said in a Sep 9 statement. In 2005 Xoma was among the first companies to receive a contract through Project BioShield, according to a previous report. Xoma reported that  its NIAID contracts cover the development of human monoclonal antibody products targeting the three most toxic serotypes of botulinum toxin, types A, B,and E. The company also said these human antibody products are expected to be safer than existing animal-derived antibodies, which it said cause serious immune reactions in some patients and vary unpredictably in their efficacy. See also: Sep 11, 2008 (CIDRAP News) – Xoma Ltd., a Berkeley, Calif., pharmaceutical company, recently announced that it received a $65 million multiyear federal contract to fund work on botulinum antitoxins, one of which it hopes to put through safety and efficacy tests starting in 2009. Clostridium botulinum, which produces botulinum toxin, a nerve poison, is among the category A agents that experts say bioterrorists would most likely try to use. However, most botulism cases are caused by tainted food or contaminated wounds. Sep 9 Xoma press release Steven Engle, Xoma’s chairman and chief executive officer, said in the statement that the contract shows the US government’s support of novel therapies that address natural, accidental, or intentional infections from pathogens and their toxins. “Since initiating its biodefense program in 2005, Xoma has used its innovative antibody technology to develop better and safe solutions,” he said. “We plan to continue working with the government’s biodefense development efforts toward future stockpiling initiatives.” Xoma said if studies show that the company’s first botulism antitoxin candidate is safe and effective and government funding continues, it would file the paperwork needed to produce the treatment for the Strategic National Stockpile. The new NIAID contract will cover the next 6 years of botulism antitoxin development, the company said. May 10, 2005, CIDRAP News story “NIAID awards first Project BioShield grants”last_img read more

Local gymnastic club offering programs for everyone

first_imgAlong with these three programs, the club also offers drop in classes, where anyone interested in participating is welcome to attend, work out with the coaches and use any of the gym’s equipment. This drop in class is not only for gymnasts; a group of snowboarders use the facility to train while there is a lack of snow on the ground.Erin Hipkiss, the club’s Recreational Coordinator, says with all the exciting programs the club’s popularity has been growing substantially. She attributes its growing attraction to a very successful summer program, which has carried over into this year.Hipkiss also spoke about the future plans for the gymnastic program, which look very promising as the club will be getting a new coach from Russia, Andrey Bekov, who has an impressive history in the sport, and currently is training some of the Junior National team.She says all of these unique experiences offered through the club are its way of “redefining what happens in the building.”Advertisement This year, the facility is offering a wide array of programs designed to cater to all levels of gymnasts, as well as all demographics interested in physical activity.Aside from regular gymnastic lessons, some of the programs offered through the club include Gymnaestrada, a combination of gymnastics and dance.Another popular choice the club’s boot camps, hour long training sessions where participants take part in a variety of exercises using the gymnastic equipment, designed for cardio, weight loss and strength training, but delivered in a fun and exciting atmosphere.- Advertisement -Currently, the club is in its third week of its boot camp program, which runs until Dec. 17 and starts up again after the New Year. The program runs Tuesdays and Thursday from 9-10 a.m. and costs $220 for the full four months. Anyone interested is encouraged to come try the program. The club is offering a first free class to get a taste of what is involved.The facility also offers a day care program for class participants, where children are supervised in a room with some of the club’s coaches.The program now offers a unique, new program called Parkour, an activity where the participant uses speed and gymnastics to creatively manoeuvre through their environment. The sport has become increasingly popular over the past few years, and is even being considered being added as an event at the X-Games.Advertisementlast_img read more

Assam Assembly results: 5 reasons why BJP won and Congress lost its bastion

first_imgThe Bharatiya Janata Party is set to form government in Assam, dislodging Tarun Gogoi from power who ruled for 15 years. While many point out towards the massive anti-incumbency factor working in favour of the BJP, the ruling party at the Centre has certainly got its gameplan to work perfectly in the northeastern state.What factors contributed to BJP’s splendid show in Assam after the humiliating shows in Delhi and Bihar?1. Campaign not micromanaged by Central leadershipUnlike Bihar and Delhi, where BJP fought the Assembly elections on PM Narendra’s Modi ‘face value’, the saffron party think tank gave more importance to the local leadership.PM Modi addressed over 40 rallies in Bihar during the Assembly election campaign in November 2015. The BJP made the massive mistake of transforming Bihar elections into a Modi vs Nitish war. Learning its lessons from Bihar, Delhi, the party tweaked its strategy limiting the number of Modi rallies in Assam.2. Projecting a strong CM candidateMonths before dates for Assam Assembly poll were announced, the BJP named Sarbananda Sonowal as its chief ministerial candidate. Sonowal, who represents Assam’s Lakhimpur constituency in the Lok Sabha, was asked to focus on resurrecting the party in his home state.As far as politics in Delhi is concerned, a win in Assam won’t matter much for the BJP as it was more of a prestige thing for the Amit Shah-led party. The BJP’s decision to pick Sonowal, who also handles the Sports and Youth Affairs ministry in the Modi cabinet, now appears to be the perfect gamble.advertisement3.  No vitriol and name calling”If by any chance the BJP is defeated in these elections, crackers will go off in celebration in Pakistan. Would you like that to happen?” Amit Shah said during a rally in Motihari while campaigning for Bihar polls.Modi’s remarks like ‘Darbhanga module’ and ‘tantrik’ jibe at Nitish’s ally Lalu didn’t go down well within the voters. Nitish utilised Modi’s taunts to set off a ‘Bihari vs Bahari’ debate, which played a big part in his win. However, in Assam, the BJP  refused to give any such opportunity to Congress. A personal attack on Tarun Gogoi was all Congress wanted, but BJP played it safe choosing not to target Gogoi or the Congress leadership.4. ‘Kingmaker’ Himanta Biswa SarmaGogoi’s once most trusted lieutenant, Himanta Biswa Sarma, walked away from Congress in August, 2015. Sarma was in Congress for nearly 23 years but he fell away with Gogoi after the Assam CM introduced his son Gaurav to politics. BJP played a masterstroke by promising the ‘respect’ Sarma expected from the Congress for being a loyal worker of the party over two decades.Sarma also disapproved of Rahul Gandhi’s handling of party matters. “Rahul Gandhi humiliated me, Tarun Gogoi humiliated me, people witnessed this. People in Assam have voted for development. The problem with Rahul Gandhi is that he is not serious. I am very happy that Rahul Gandhi has got his lesson,” Sarma told India Today.”Till Congress replaces the ‘blue blood culture’, the party has no future,” Sarma, who political analysts describe as Assam’s kingmaker, said.5. Issues of illegal immigrants and porous borderThe BJP released its vision document for Assam assembly elections in March, a month before polls in the northeastern state.Naming the document ‘BJP Assam Vision Document 2016-2025’, the party promised to deliver on sensitive issues like foreign nationals and porous border with Bangladesh. BJP made its local leaders focus on the issue of construction of fence along the 4,000km long border with Bangladesh during campaigning.It also assured the people that a law would be enacted to “deal sternly” with industries, businesses, small and medium enterprises or any other agencies employing infiltrators. INTERACTIVE MAP: RESULTS BY CONSTITUENCYAssam | West Bengal | Tamil Nadu | Kerala | Puducherrylast_img read more

Another Cancun pizzeria closes its doors due to repeated robberies

first_imgCancun, Q.R. — Continued robberies and other violent offenses have caused the closure of a well-known Cancun restaurant.Long time Italian restaurant owners of El Tigre and El Toro closed their doors on Cancun Avenue and La Costa Avenue due to a wave of assaults they have suffered in recent months.In a public statement, the restaurant owner says that so far this year, they have been robbed once a week, which has resulted in them closing both of their Cancun restaurants.“There is no business that can sustain a theft per week,” the statement says, “So far this year we have been assaulted and robbed once a week.”They ask different agencies to take action in order to end the insecurity in Cancun.“Hopefully this wills serve as a call to the relevant authorities, not only to serve as such, but to understand, at all levels, that, between insecurity, crime, corruption, and sometimes incomprehensible, arbitrary and contradictory procedures bureaucratic to which the operation of a trade is subordinated, it is exhaustingly complicated to undertake and sustain a business in this city,” the statement said.“We would like to thank the people who accompanied us during these years, for their preference,” the statement said.In March of last year, Pizza Del Perro Negro Cancún also closed their doors after an attack left several staff injured.They announced a similar statement saying, “Jauría and I have made the decision to close Pizza Del Perro Negro Cancún. I hope I have left a mark on you and have sown the seed of love in your hearts. I know you will not forget my pizza and that’s why when the waters calm down and times are better to harvest, I’ll come back with new stories to write. Thanks Cancun for so much!”Click to share on Facebook (Opens in new window)Click to share on Twitter (Opens in new window)Click to share on LinkedIn (Opens in new window)Click to share on WhatsApp (Opens in new window)last_img read more